International journal of radiation oncology, biology, physics
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Int. J. Radiat. Oncol. Biol. Phys. · Nov 2004
Long-term results using local excision after preoperative chemoradiation among selected T3 rectal cancer patients.
To assess the pelvic failure among patients with T3 rectal cancer treated with local excision after preoperative chemoradiation. ⋯ In an experience stimulated by patient refusal of APR, highly selected patients who responded well to conventional external-beam radiotherapy (CXRT) were selected to undergo local excision. Most of these patients had pathologic complete response. Local control and survival rates are comparable to those achieved with chemoradiation followed by mesorectal excision. This strategy should be prospectively studied in a group of patients with low rectal cancer who have no clinical evidence of tumor after chemoradiation.
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Int. J. Radiat. Oncol. Biol. Phys. · Nov 2004
Reproducibility of organ position using voluntary breath-hold method with spirometer for extracranial stereotactic radiotherapy.
To evaluate in healthy volunteers the reproducibility of organ position using a voluntary breath-hold method with a spirometer and the feasibility of this method for extracranial stereotactic radiotherapy in a clinical setting. ⋯ The voluntary breath-hold method with a spirometer is feasible, with relatively good reproducibility. We are encouraged about the use of this technique clinically for extracranial stereotactic radiotherapy.
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Int. J. Radiat. Oncol. Biol. Phys. · Nov 2004
Randomized Controlled Trial Multicenter Study Clinical TrialEffect of oral sucralfate on late rectal injury associated with radiotherapy for prostate cancer: A double-blind, randomized trial.
To assess whether oral sucralfate is effective in preventing late rectal injury in prostate cancer patients treated with radiotherapy. ⋯ This trial demonstrated no statistically significant reduction in the incidence of late rectal toxicity in patients randomized to receive sucralfate. However, this result was considered inconclusive, because the trial was unable to exclude clinically important differences in the late toxicity rates.
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Int. J. Radiat. Oncol. Biol. Phys. · Nov 2004
Multicenter Study Comparative StudyPatterns of radiotherapy practice for patients with carcinoma of the uterine cervix: a patterns of care study.
To determine the influence of research findings and evolving technology on the practice of radiotherapy in patients with carcinoma of the cervix. ⋯ The sharp increase in the use of chemotherapy in 1999 suggested rapid application of the results from randomized trials. However, considerable heterogeneity in practice patterns remains, particularly in the use of brachytherapy. The practice at small facilities appears to differ significantly from that at larger facilities in several respects, with a statistically significantly larger proportion of treatments at small facilities failing to meet current guidelines for optimal treatment.
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Int. J. Radiat. Oncol. Biol. Phys. · Nov 2004
Practice Guideline GuidelineProposed guidelines for image-based intracavitary brachytherapy for cervical carcinoma: report from Image-Guided Brachytherapy Working Group.
To present issues to be considered in, and make proposals for, image-based brachytherapy for cervical cancer. ⋯ Although current institutional brachytherapy prescription for cervical cancer should continue, image-based data collection and analysis are needed to optimize cervical cancer brachytherapy. Proposals are made for research in image-based brachytherapy for cervical cancer.