International journal of radiation oncology, biology, physics
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Int. J. Radiat. Oncol. Biol. Phys. · Sep 2011
Multicenter Study Comparative StudyHelical tomotherapy versus single-arc intensity-modulated arc therapy: a collaborative dosimetric comparison between two institutions.
Both helical tomotherapy (HT) and single-arc intensity-modulated arc therapy (IMAT) deliver radiation using rotational beams with multileaf collimators. We report a dual-institution study comparing dosimetric aspects of these two modalities. ⋯ Both techniques created highly conformal plans that met or exceeded the planning goals. The delivery time and total monitor units were lower in RA than in HT plans, whereas HT provided higher target dose uniformity.
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Int. J. Radiat. Oncol. Biol. Phys. · Sep 2011
Long-term outcomes of patients with spinal cord gliomas treated by modern conformal radiation techniques.
This study retrospectively examines the long-term therapeutic outcomes of 32 patients with primary spinal cord gliomas at Massachusetts General Hospital between 1991 and 2005 treated by either photon intensity-modulated radiotherapy or conformal proton radiotherapy. ⋯ For patients with spinal cord gliomas, significant factors associated with patient outcome include tumor pathology, age, extent of surgery, and treatment.
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Int. J. Radiat. Oncol. Biol. Phys. · Sep 2011
Chest wall Ewing sarcoma family of tumors: long-term outcomes.
To review the 40-year University of Florida experience treating Ewing sarcoma family of tumors of the chest wall. ⋯ This is the largest single-institution series describing the treatment of chest wall Ewing tumors. Despite improvements in survival, obtaining local control is challenging and often accompanied by morbidity. Effort should be focused on identifying tumors amenable to combined-modality local therapy and to improving RT techniques.
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Int. J. Radiat. Oncol. Biol. Phys. · Aug 2011
Comparative StudyHelical tomotherapy vs. intensity-modulated proton therapy for whole pelvis irradiation in high-risk prostate cancer patients: dosimetric, normal tissue complication probability, and generalized equivalent uniform dose analysis.
To compare intensity-modulated proton therapy (IMPT) and helical tomotherapy (HT) treatment plans for high-risk prostate cancer (HRPCa) patients. ⋯ Comparable PTV coverage was observed. Based on NTCP calculation, IMPT is expected to allow a small reduction in rectal toxicity, and a significant dosimetric gain with IMPT, both in medium-dose and in low-dose range in all OARs, was observed.