International journal of radiation oncology, biology, physics
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Int. J. Radiat. Oncol. Biol. Phys. · May 2011
Intensity-modulated radiotherapy for locally advanced non-small-cell lung cancer: a dose-escalation planning study.
To evaluate the potential for dose escalation with intensity-modulated radiotherapy (IMRT) in positron emission tomography-based radiotherapy planning for locally advanced non-small-cell lung cancer (LA-NSCLC). ⋯ In LA-NSCLC, IMRT offers the potential to significantly escalate the PD, dependent on the lung and spinal cord tolerance. However, parallel increases in the esophageal dose abolished the advantage, even when using collapsed cone algorithms. This is important to consider in the context of concomitant chemoradiotherapy schedules using IMRT.
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Int. J. Radiat. Oncol. Biol. Phys. · May 2011
Rectal motion in patients receiving preoperative radiotherapy for carcinoma of the rectum.
To assess the movement of rectum, mesorectum, and rectal primary during a course of preoperative chemoradiotherapy. ⋯ Contrast is no longer used in CT simulation. Assuming bony alignment, a nonuniform margin of 8 mm anteriorly, 9 mm posteriorly, and 8 mm left and right is recommended.
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Int. J. Radiat. Oncol. Biol. Phys. · Apr 2011
Randomized Controlled TrialMometasone furoate effect on acute skin toxicity in breast cancer patients receiving radiotherapy: a phase III double-blind, randomized trial from the North Central Cancer Treatment Group N06C4.
A two-arm, double-blind, randomized trial was performed to evaluate the effect of 0.1% mometasone furoate (MMF) on acute skin-related toxicity in patients undergoing breast or chest wall radiotherapy. ⋯ Patients receiving daily MMF during radiotherapy might experience reduced acute skin toxicity compared with patients receiving placebo.