International journal of radiation oncology, biology, physics
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Int. J. Radiat. Oncol. Biol. Phys. · Nov 2015
Stress and Burnout Among Residency Program Directors in United States Radiation Oncology Programs.
To evaluate stressors among radiation oncology residency program directors (PDs) and determine the prevalence and indicators of burnout. ⋯ Moderate levels of burnout are common in U.S. radiation oncology PDs with regulatory stressors being common. Despite this, many PDs are fulfilled with their role. Longitudinal studies assessing dynamic external factors and their influence on PD burnout would be beneficial.
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Int. J. Radiat. Oncol. Biol. Phys. · Nov 2015
Randomized Controlled Trial Comparative StudyA Randomized Phase 2 Study Comparing 2 Stereotactic Body Radiation Therapy Schedules for Medically Inoperable Patients With Stage I Peripheral Non-Small Cell Lung Cancer: NRG Oncology RTOG 0915 (NCCTG N0927).
To compare 2 stereotactic body radiation therapy (SBRT) schedules for medically inoperable early-stage lung cancer to determine which produces the lowest rate of grade ≥3 protocol-specified adverse events (psAEs) at 1 year. ⋯ 34 Gy in 1 fraction met the prespecified criteria and, of the 2 schedules, warrants further clinical research.
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Int. J. Radiat. Oncol. Biol. Phys. · Nov 2015
Combined Ventilation and Perfusion Imaging Correlates With the Dosimetric Parameters of Radiation Pneumonitis in Radiation Therapy Planning for Lung Cancer.
The purpose of this study was to prospectively investigate clinical correlations between dosimetric parameters associated with radiation pneumonitis (RP) and functional lung imaging. ⋯ RP dosimetric parameters correlated significantly with functional lung imaging.
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Int. J. Radiat. Oncol. Biol. Phys. · Nov 2015
Observational StudyRadical Radiation Therapy After Lung-Sparing Surgery for Malignant Pleural Mesothelioma: Survival, Pattern of Failure, and Prognostic Factors.
To prospectively assess the survival, patterns of failure, and prognostic factors in a large cohort of patients with malignant pleural mesothelioma who had undergone a novel trimodal therapeutic approach, including lung-sparing surgery, chemotherapy, and subsequent treatment with high doses of intensity modulated radiation therapy (IMRT) to the whole hemithorax. ⋯ Radical IMRT after lung-sparing surgery and chemotherapy for malignant pleural mesothelioma leads to promising survival results and acceptable toxicity rates. The similarity of survival between patients treated with extended P/D or partial pleurectomy observed in our study is intriguing.
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Int. J. Radiat. Oncol. Biol. Phys. · Nov 2015
Randomized Controlled Trial Multicenter StudyQuality of Life in Relation to Pain Response to Radiation Therapy for Painful Bone Metastases.
To study quality of life (QoL) in responders and nonresponders after radiation therapy for painful bone metastases; and to identify factors predictive for a pain response. ⋯ Responding patients show a better QoL after radiation therapy for painful bone metastases than nonresponders. Our model did not have enough discriminative power to predict which patients are likely to respond to radiation therapy. Therefore, radiation therapy should be offered to all patients with painful bone metastases, aiming to decrease pain and improve QoL.