Indian journal of pathology & microbiology
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Indian J Pathol Microbiol · Jul 2002
Human toxocariasis and ascariasis: concomitant parasitism in Srinagar, Kashmir, India.
Human toxocariasis caused by Toxocara canis is common in both developing and developed countries and leads to visceral larva migrans with high morbidity and mortality. Ascariasis caused by Ascaris lumbricoides, too has global distribution and in India, high prevalence rate has been reported in Kashmir (J & K State). Both nematode parasites, Toxocara canis and A. lumbricoides require similar biological and environmental conditions for the development of eggs in soil. ⋯ However, one ascariasis patient studied in the age group of 1-10 years (4 years old) had also positive antibody response to T. Canis antigen. This study is the first report of human toxocariasis in Kashmir, India, an endemic zone for ascariasis and emphasizes the need for detailed epidemiological study for the ultimate prevention and control of this disease
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Indian J Pathol Microbiol · Jul 2002
Profile of transfusion transmissible infections and associated risk factors among blood donors of Kerala.
Blood transfusion is an important mode of transmission of infections to the recipient. The aim of the study was to assess the prevalence of transfusion transmissible infections and the possible risk factors among blood donors. During the study period (1994-99) donor samples were screened for HBsAg, HIV, HCV and Syphilis. ⋯ Seropositivity for HIV is relatively low compared to similar studies conducted in other regions of the country. This finding is attributed to the pre donation counseling in donor selection. An important outcome of the study is that Class III donors form a high-risk group for transfusion transmissible infections.
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Indian J Pathol Microbiol · Jan 2002
Case ReportsHistiocytic necrotizing lymphadenitis (Kikuchi Fujimoto Disease)--a report of four cases.
Four cases of histiocytic necrotizing lymphadenitis without granulocytic infiltration (Kikuchi-Fujimoto Disease) are described. All the cases were seen in young women who presented with cervical lymphadenopathy with mild or no fever. Histology of the lymphnode revealed paracortical necrotizing lesions with abundant karyorrhexis. ⋯ Diagnosis of Kikuchi-Fujimoto disease was considered after ruling out connective tissue disorders. Three of the four cases that were followed up showed a self-limiting course. It is important to differentiate this rare cause of febrile disease with enlargement of lymphnodes, from other causes of febrile disease with enlargement of lymphnodes, from other causes of lymphadenopathy, especially lymphoma.
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Indian J Pathol Microbiol · Jul 2001
Rapid identification of fluconazole resistance using Chrom agar Candida.
All though extremely rare 10 years ago, antifungal drug resistance is becoming a major problem in certain populations, especially in those infected with HIV. This study was undertaken to study the resistance of Candida species isolated in our hospital to Fluconazole using Chrom agar Candida. ⋯ The MIC of the 16 strains were done using RPMI 1640 medium by macro broth dilution method. MIC of 9 strains was 64 & > 64 ug/ml of 6 strains 32 ug/ml and 1 strain 16 ug/ml.
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Indian J Pathol Microbiol · Apr 2001
Polymerase chain reaction using IS6110 primer to detect Mycobacterium tuberculosis in clinical samples.
Nucleic acid amplification using IS6110 primers to detect Mycobacterium tuberculosis in clinical specimens has been extensively used as laboratory tool for the diagnosis for tuberculosis. Despite it's dramatic scientific value in practice, it is not as sensitive as expected for the detection of M. tuberculosis. The results of the study suggest that PCR using 123 bp fragment of DNA belonging to IS6110 is specific (95.6%) but only has a sensitivity of 30% to detect M. tuberculosis in clinical specimens.