Indian journal of pathology & microbiology
-
Indian J Pathol Microbiol · Jan 2018
Evaluation of procalcitonin as a diagnostic marker in neonatal sepsis.
Neonatal sepsis is an early infection occurring within 28 days of the postnatal life. It has nonspecific signs and symptoms which make the diagnosis cumbersome. It inflicts an increase in morbidity and mortality among neonates. Procalcitonin (PCT) is yet another acute phase reactant, which is synthesized by the C-cells of thyroid gland. ⋯ PCT may not be sufficiently used as a sole marker of sepsis in neonates compared to CRP. PCT in conjunction with CRP and other tests for septic screen can aid in better diagnosis of neonatal sepsis.
-
Indian J Pathol Microbiol · Oct 2015
Case ReportsPrimary intracardiac malignant peripheral nerve sheath tumor: A rare case report.
Myxomas are the most common benign cardiac tumors constituting approximately 75% of all the cardiac tumors. Rest 25% are malignant and sarcomas being the commonest. ⋯ Clinical signs and symptoms depend on the location and extent of involvement. Complete resection is the treatment of choice but local recurrence is common.
-
Indian J Pathol Microbiol · Oct 2015
Observational StudyAssociation of virulence genes with mecA gene in Staphylococcus aureus isolates from Tertiary Hospitals in Nigeria.
Staphylococcus aureus is the etiological agent for a wide range of human infections, and its pathogenicity largely depends on various virulence factors associated with adherence, evasion of the immune system and damage of the host. This study determined the prevalence of methicillin-resistant S. aureus (MRSA) and some selected virulence genes in clinical isolates of S. aureus from South-Western Nigeria. ⋯ The study concluded that there is a high prevalence of MRSA in Nigeria with association of eta and icaA genes with mecA gene in S. aureus isolates.