Clinical and experimental dermatology
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Clin. Exp. Dermatol. · Jun 2009
Efalizumab treatment of psoriasis vulgaris: a cohort study in outpatient clinical practice.
Efalizumab is approved by the European Medicines Evaluation Agency for the treatment of adult patients with moderate to severe plaque psoriasis who fail to respond to, have a contraindication for, or cannot tolerate other systemic therapies. ⋯ Efalizumab is an effective and safe treatment for psoriasis in most patients of a high need population in routine practice, and provides maintained improvement in 'responders'. Combination treatment was transiently used in 48.4% of patients to optimize therapeutic results. Special consideration must be given to possible rebound in patients with an inadequate response or after discontinuation of treatment.
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Clin. Exp. Dermatol. · Jun 2009
Letter Review Case ReportsHerpes zoster complicated by delayed intracranial haemorrhage.
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Clin. Exp. Dermatol. · Apr 2009
ReviewOral ulcers: clinical aspects. A tool for dermatologists. Part I. Acute ulcers.
Oral ulcers are generally painful lesions that are related to various conditions developing within the oral cavity. They can be classified as acute or chronic according to their presentation and progression. ⋯ The correct differential diagnosis is necessary to establish the appropriate treatment, taking into account all the possible causes of ulcers in the oral cavity. In the first part of this two-part review, acute oral ulcers are reviewed.