Archives of pathology & laboratory medicine
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Arch. Pathol. Lab. Med. · Apr 1981
Case ReportsSoft-tissue sarcoma of undetermined histogenesis: an ultrastructural study.
A certain proportion of soft-tissue sarcomas are difficult to classify accurately. In this case report, initial light microscope observations of a soft-tissue tumor suggested a diagnosis of a monophasic synovial sarcoma. However, critical evaluation of the histologic features, results of studies with special stains, and ultrastructural observations indicated that this tumor is best categorized as an undifferentiated soft-tissue sarcoma of "undetermined histogenesis."
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Arch. Pathol. Lab. Med. · Jul 1980
Case ReportsMetastases to primary intracranial meningiomas and neurilemomas.
Five cases of carcinoma metastatic to intracranial meningioma or neurilemoma are presented and compared with 20 similar cases reported in the literature. The phenomenon was most often seen on autopsy (17 of 25 cases) and was found more commonly in females (3:2), with nearly 90% of donor cancers being found in breast or lung. The existence of the donor tumor, which was always found to be widely disseminated, was known prior to autopsy in only half the cases.
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Arch. Pathol. Lab. Med. · Jul 1980
Case ReportsPulmonary hemorrhage and immune-complex deposition in the lung. Complications in a patient with systemic lupus erythematosus.
A patient with systemic lupus erythematosus (LE) was admitted with an acute illness characterized by dyspnea, hemoptysis, fever, and diffuse infiltrates revealed by chest roentgenograms. An open-lung biopsy specimen showed massive intrapulmonary hemorrhage, and immunofluorescence and electron microscopic examinations showed granular deposits of IgG within the alveolar walls and pulmonary vessels. ⋯ Her condition again improved over several days, and she has had no pulmonary symptoms for nine months. In some instances, pulmonary hemorrhage in patients with systemic LE may be mediated by polymorphonuclear leukocytes attracted by immune-complex deposits.
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Aneurysms of the ulnar artery are most common secondary to blunt trauma to the hypothenar eminence. The anatomic relationship between the superficial branch of the ulnar artery and the hook of the hamate exposes this segment of the artery to injury. The clinical, roentgenographic, and pathologic features of two patients, one with an acute traumatic episode and one with chronic trauma are presented. ⋯ Thrombosis of the aneurysm and adjacent arterial segment seemed to be related to the onset of the ischemic symptoms. Digital artery embolization can complicate the thrombotic episode. Although surgical intervention may correct the ischemic symptoms, prevention via industrial education seems to be the best form of management.
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Two cases of vasitis nodosa, one typical example and one unusual case, are presented. The first case was a complication of a previous vasectomy, manifested as a painful nodule at the site of previous surgery, and was associated with sperm granulomas. In the second case, no antecedent vasectomy had been performed, the lesion was located deep in the scrotum, and inflammation was scant. ⋯ In such cases, the diagnosis of vasitis nodosa can be resolved by finding spermatozoa within the proliferating ductules and individual epithelial cells. Electron microscopy can also be useful in eliminating the possibility that the nature of the proliferating cells is mesothelial. However, the etiology of vasitis nodosa in the absence of previous local traumatic or inflammatory insults remains obscure.