Spine
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Comparative Study
New formulations of demineralized bone matrix as a more effective graft alternative in experimental posterolateral lumbar spine arthrodesis.
A rabbit model of posterolateral intertransverse process spine arthrodesis was used. ⋯ The new flexible sheet and malleable putty forms of demineralized bone matrix were effective as graft extender and graft enhancer in a model of posterolateral lumbar spine fusion. These newer formulations of Grafton appear to have a greater capacity to form bone than the gel form or autogenous bone graft alone in this model.
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An analysis of the geometric data of the lumbar spine in Chinese men. Lateral radiographs were obtained of 16 men in the upright position to a trunk flexion of 90 degrees in 30 degrees increments. ⋯ No obvious interracial differences were found in the geometric data found in this study, which suggests that morphometric data obtained from Caucasian individuals may be applied to Chinese patients for clinical purposes.
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Randomized Controlled Trial Comparative Study Clinical Trial
Influence of estrogen-progestin treatment on back pain and disability among slim premenopausal women with low lumbar spine bone mineral density. A 2-year placebo-controlled randomized trial.
A 2-year randomized controlled trial. ⋯ It seems that this regimen may have alleviating effects on nighttime back pain and functional back disability in slim osteopenic premenopausal women.
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Comparative Study
The use of recombinant human bone morphogenetic protein 2 (rhBMP-2) to promote spinal fusion in a nonhuman primate anterior interbody fusion model.
A study on the efficacy of recombinant human bone morphogenetic protein 2 (rhBMP-2) in a nonhuman primate anterior interbody fusion model. ⋯ This study was able to document the efficacy of rhBMP-2 with an absorbable collagen sponge carrier and a cortical dowel allograft to promote anterior interbody fusion in a nonhuman primate model at a dose of 0.4 mg per implant site (1.5 mg/mL concentration). The late of new bone formation and fusion with the use of rhBMP-2 and cortical dowel allograft appears to be far superior to that of autogenous cancellous iliac crest graft with cortical dowel allograft.
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Comparative Study
Pedicle and transverse process screws of the upper thoracic spine. Biomechanical comparison of loads to failure.
An In vitro biomechanical load-to-failure test. ⋯ Upper thoracic pedicle screws have superior axial loading characteristics compared with bicortical transverse process screws, except at T1. Load behavior of either of these screws was not predictable based on anatomic parameters.