Spine
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Comparative Study
The use of recombinant human bone morphogenetic protein 2 (rhBMP-2) to promote spinal fusion in a nonhuman primate anterior interbody fusion model.
A study on the efficacy of recombinant human bone morphogenetic protein 2 (rhBMP-2) in a nonhuman primate anterior interbody fusion model. ⋯ This study was able to document the efficacy of rhBMP-2 with an absorbable collagen sponge carrier and a cortical dowel allograft to promote anterior interbody fusion in a nonhuman primate model at a dose of 0.4 mg per implant site (1.5 mg/mL concentration). The late of new bone formation and fusion with the use of rhBMP-2 and cortical dowel allograft appears to be far superior to that of autogenous cancellous iliac crest graft with cortical dowel allograft.
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Comparative Study
New formulations of demineralized bone matrix as a more effective graft alternative in experimental posterolateral lumbar spine arthrodesis.
A rabbit model of posterolateral intertransverse process spine arthrodesis was used. ⋯ The new flexible sheet and malleable putty forms of demineralized bone matrix were effective as graft extender and graft enhancer in a model of posterolateral lumbar spine fusion. These newer formulations of Grafton appear to have a greater capacity to form bone than the gel form or autogenous bone graft alone in this model.
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Comparative Study
One-stage decompression and posterolateral and interbody fusion for severe spondylolisthesis. An analysis of 14 patients.
A retrospective study of 14 patients with high-grade L5-S1 spondylolisthesis surgically treated with one-stage decompression and posterolateral and interbody fusion (technique of Bohlman and Cook). ⋯ Posterior decompression of the spinal canal combined with anterior and posterior arthrodesis performed at one stage through a posterior approach is a safe and effective technique for managing severe spondylolisthesis.
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An analysis of the change in strain distribution of intervertebral discs present after anterior cervical decompression and fusion by an original method. The analytical results were compared to occurrence of herniation of the intervertebral disc on magnetic resonance imaging. ⋯ Close attention should be paid to long-term biomechanical changes in the unfused segment.
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An analysis of the geometric data of the lumbar spine in Chinese men. Lateral radiographs were obtained of 16 men in the upright position to a trunk flexion of 90 degrees in 30 degrees increments. ⋯ No obvious interracial differences were found in the geometric data found in this study, which suggests that morphometric data obtained from Caucasian individuals may be applied to Chinese patients for clinical purposes.