Spine
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A retrospective study on 24 patients with acute central cervical cord injury caused by traumatic disc herniation. ⋯ Far more common than previously expected, acute disc herniation in cervical spine injury is the one of principal cause for central cord syndrome. Magnetic resonance imaging assessment and surgical intervention are required.
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Randomized Controlled Trial Multicenter Study Clinical Trial
The use of rhBMP-2 in interbody fusion cages. Definitive evidence of osteoinduction in humans: a preliminary report.
A prospective randomized controlled human clinical pilot trial. ⋯ The arthrodesis was found to occur more reliably in patients treated with rhBMP-2-filled fusion cages than in controls treated with autogenous bone graft, although the sample size was limited. There were no adverse events related to the rhBMP-2 treatment. This study is one of the first to show consistent and unequivocal osteoinduction by a recombinant growth factor in-humans.
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Clinical Trial
Management of chronic discogenic low back pain with a thermal intradiscal catheter. A preliminary report.
A prospective nonrandomized clinical trial. ⋯ A statistically significant improvement in functional outcome was obtained in patients with chronic discogenic low back pain treated thermally by the SpineCath.
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Bone mineral density variations throughout the sacrum were measured and correlated with sacral screw insertion torque. ⋯ This study quantified the volumetric bone mineral density variations within the S1 body and ala, and a significant linear correlation between the screw insertion torque and bone mineral density was found. Optimal sacral screw insertion pathways were also outlined based on bone mineral density values.
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An analysis of 44 cauda equina syndrome cases. ⋯ The data strongly support the management of cauda equina syndrome from lumbar disc herniation as a diagnostic and surgical emergency.