Spine
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An analysis of 44 cauda equina syndrome cases. ⋯ The data strongly support the management of cauda equina syndrome from lumbar disc herniation as a diagnostic and surgical emergency.
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Randomized Controlled Trial Multicenter Study Clinical Trial
The use of rhBMP-2 in interbody fusion cages. Definitive evidence of osteoinduction in humans: a preliminary report.
A prospective randomized controlled human clinical pilot trial. ⋯ The arthrodesis was found to occur more reliably in patients treated with rhBMP-2-filled fusion cages than in controls treated with autogenous bone graft, although the sample size was limited. There were no adverse events related to the rhBMP-2 treatment. This study is one of the first to show consistent and unequivocal osteoinduction by a recombinant growth factor in-humans.
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Clinical Trial
Management of chronic discogenic low back pain with a thermal intradiscal catheter. A preliminary report.
A prospective nonrandomized clinical trial. ⋯ A statistically significant improvement in functional outcome was obtained in patients with chronic discogenic low back pain treated thermally by the SpineCath.
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An anatomic study of the cervical intervertebral foramina, nerve roots, and intradural rootlets performed using a surgical microscope. ⋯ This study demonstrated the anatomy of the nerve roots, rootlets, and intervertebral foramina, and may aid in understanding the pathology of cervical radiculopathy. The presence of intradural connections between dorsal nerve roots and the relation between the course of the nerve root and the intervertebral disc may explain the clinical variation of symptoms resulting from-nerve root compression in the cervical spine. To perform cervical foraminotomy for cervical radiculopathy, it is necessary to understand the detailed anatomy of the intervertebral foramina thoroughly.
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A retrospective study on 24 patients with acute central cervical cord injury caused by traumatic disc herniation. ⋯ Far more common than previously expected, acute disc herniation in cervical spine injury is the one of principal cause for central cord syndrome. Magnetic resonance imaging assessment and surgical intervention are required.