Spine
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Comparative Study
Results of skip laminectomy-minimum 2-year follow-up study compared with open-door laminoplasty.
Results of skip laminectomy and open-door laminoplasty for cervical spondylotic myelopathy were compared. ⋯ Skip laminectomy was less invasive to the posterior extensor mechanism including the deep extensor muscles than open-door laminoplasty. This new procedure was effective in preventing postoperative morbidities often seen after conventional laminectomy and laminoplasty with adequate decompression of the spinal cord.
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Multicenter Study Clinical Trial
Intermediate follow-up after treatment of degenerative disc disease with the Bryan Cervical Disc Prosthesis: single-level and bi-level.
Prospective, concurrently enrolled, multicenter trials of the Bryan Cervical Disc Prosthesis (Medtronic Sofamor Danek, Memphis, TN) were conducted for the treatment of patients with single-level and two-level (bi-level) degenerative disc disease of the cervical spine. ⋯ Clinical success for both studies exceeded the study acceptance criteria of 85%. At 1-year follow-up, the flexion-extension range of motion per level: Discectomy and implantation of the device alleviates neurologic symptoms and signs similar to anterior cervical discectomy and fusion. Radiographic evidence supports maintenance of motion. The procedure is safe and the patients recover quickly. At least 5 years of follow-up will be needed to assess the long-term functionality of the prosthesis and protective influence on adjacent levels.
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In vitro experiment using bone morphogenetic protein-2 (BMP-2) and human intervertebral disc (IVD) cells. ⋯ The rhBMP-2 clearly up-regulated mRNA expression of chondrogenic components and also stimulated proteoglycan synthesis without expression of osteogenic phenotype. Taken together, this study raise the possibility of rhBMP-2 can be anabolic agent for regenerating matrix of intervertebral disc.
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Case Reports
Thoracic neurenteric cyst in a middle aged adult presenting with Brown-Sequard syndrome.
To report an unusual presentation of a thoracic neurenteric cyst. ⋯ Intraspinal neuroenteric cyst without plain vertebral anomaly may occur after trauma in middle aged adult life with Brown-Sequard syndrome. Successful treatment requires early recognition of those cysts and their associated abnormalities.