Spine
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Randomized Controlled Trial Clinical Trial
Efficacy and safety of rofecoxib in patients with chronic low back pain: results from two 4-week, randomized, placebo-controlled, parallel-group, double-blind trials.
Two replicate, 4-week, randomized, double-blind, placebo-controlled, trials of rofecoxib 25 and 50 mg versus placebo for chronic low back pain. ⋯ Rofecoxib significantly reduced chronic low back pain in adults and was well tolerated.
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Randomized Controlled Trial Comparative Study Clinical Trial
Level of distress in a recurrent low back pain population referred for physical therapy.
Recruitment phase of a randomized clinical trial. ⋯ Distress associated with low back pain is common with one third of patients referred for physical therapy at the units studied exhibiting a level of distress that increased their relative risk of poor outcome by 3 to 4 times. Clinically, screening this group of patients may help indicate when liaison with other professionals is appropriate and possibly identify those patients who may be too distressed to respond to physical therapy intervention alone.
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A retrospective cohort study with cross-sectional outcome analysis of patients who underwent anterior column reconstruction with a titanium mesh cage after single-level or multilevel thoracic or lumbar vertebrectomy. ⋯ The cylindrical mesh titanium cage is a successful adjunct in restoring and maintaining sagittal plane alignment after thoracolumbar vertebrectomy and, in this context, provides an effective method for anterior column reconstruction.
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Prospective cohort study. Victims of car accidents who initiated compensation claim procedures at a Dutch insurance company and presented themselves with neck complaints were sent a questionnaire containing neck-related questions and questions regarding the coping styles used shortly after the accident. An additional two questionnaires were administered 6 and 12 months, respectively, after the accident. ⋯ The coping style during the first few weeks after the accident and the gender are related to the duration of neck complaints (Cox regression: palliative handling relative risk = 0.91, P = 0.002; seeking social support relative risk = 1.06, P = 0.042; and gender relative risk = 1.50, P = 0.036). Thereafter the intensity of somatic complaints plays a role. Paying attention to the coping style could contribute to the prevention of the development of late whiplash syndrome.
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A cross-sectional study of 745 young adolescents in the area of two Regional Health Centers in the Netherlands. ⋯ Psychosomatic factors appear to be more strongly related to the occurrence of neck and/or shoulder and back complaints than the type and weight of the schoolbag and other physical factors. The role of psychosomatic factors should be further explored in future longitudinal research.