Spine
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Details of presentation and approach to the treatment of scoliosis in a case of a Rigid Spine Syndrome (RSS). ⋯ The chromosomal bases of CMD and characteristic features of RSS, including diagnostic tests, have been reviewed. Surgical intervention with spinal deformity fusion, correction, and instrumentation is indicated in RSS with progressive spinal imbalance not responding to conservative therapy is safe and can give promising results.
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Giovanni Alfonso Borelli is often described as the father of biomechanics. He was born in Naples in 1608. ⋯ Borelli died in Rome on December 31, 1679, but his impressive body of original work helped inspire a great number of future scientists, microscopists, and inventors. The highest honor bestowed by the American Society of Biomechanics is the Giovanni Borelli Award.
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We investigated the extracellular signal-regulated kinase (ERK) activation by immunohistochemically detecting phosphorylated ERK (pERK) in the dorsal root ganglion (DRG) and spinal cord. ⋯ Profiles of pERK induction in neurons after DRG injury were similar between the DRG and spinal cord, whereas pERK induction in the satellite cells was more long lasting. The pERK induction in Schwann cells in the DRG was late onset and the most long lasting.
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Spine loads associated with lifting a 9-kg weight were estimated at three torso flexion angles (0 degrees, 22.5 degrees, and 45 degrees), and lumbosacral motion segments were cyclically loaded using these loads until failure or to a maximum of 10,020 cycles. ⋯ Fatigue failure of spinal tissues can occur rapidly when the torso is fully flexed during occupational lifting tasks; however, many thousands of cycles can be tolerated in a neutral posture. Future lifting recommendations should be sensitive to rapid development of fatigue failure in torso flexion.
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Pinealectomy was used to induce scoliosis in Broiler chickens, and a histologic investigation of the pinealectomized chickens was performed. ⋯ The results show that the incidence of scoliosis using pinealectomized Broiler chickens is sufficient to study histologic changes of the vertebral body before onset of scoliosis. We found that the osteoclast number and trabecular thickness increased in pinealectomized chickens after 3 days after surgery, just before scoliosis began to develop, and that no change in the growth plate occurred. This suggests that there is no association between changes in the growth plate and the development of scoliosis. However, the change in osteoclast number may have an association with the development of scoliosis, through changes in bone modeling.