Spine
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Randomized Controlled Trial Multicenter Study Comparative Study
Surgical or nonoperative treatment for lumbar spinal stenosis? A randomized controlled trial.
A randomized controlled trial. ⋯ Although patients improved over the 2-year follow-up regardless of initial treatment, those undergoing decompressive surgery reported greater improvement regarding leg pain, back pain, and overall disability. The relative benefit of initial surgical treatment diminished over time, but outcomes of surgery remained favorable at 2 years. Longer follow-up is needed to determine if these differences persist.
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A systematic review of randomized controlled trials. ⋯ Harpagophytum procumbens, Salix alba, and Capsicum frutescens seem to reduce pain more than placebo. Additional trials testing these herbal medicines against standard treatments will clarify their equivalence in terms of efficacy. The quality of reporting in these trials was generally poor; thus, trialists should refer to the CONSORT statement in reporting clinical trials of herbal medicines.
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Comparative Study
Biomechanical evaluation of the Total Facet Arthroplasty System: 3-dimensional kinematics.
An in vitro biomechanical study to quantify 3-dimensional kinematics of the lumbar spine following facet arthroplasty. ⋯ The TFAS allowed considerable motion in all directions tested, with ROM being less than the intact in flexion and lateral bending, and greater than the intact in axial rotation. The helical axis of motion with the TFAS was not different from intact in flexion-extension and lateral bending, but it was shifted anteriorly in axial rotation. The kinematics of the TFAS were more similar to the intact spine than were the kinematics of the posterior fixation when applied to a destabilized lumbar spine.
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Comparative Study
Active lifestyle protects against incident low back pain in seniors: a population-based 2-year prospective study of 1387 Danish twins aged 70-100 years.
Prospective cohort study of twins. ⋯ Strenuous physical activity at least once a week is protective for incident LBP in seniors.
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Comparative Study
Q89R polymorphism in the LDL receptor-related protein 5 gene is associated with spinal osteoarthritis in postmenopausal Japanese women.
An association study investigating the genetic etiology for spinal osteoarthritis. ⋯ We suggest that a genetic variation at the LRP5 gene locus is associated with spinal osteoarthritis, in line with the involvement of the LRP5 gene in the bone and cartilage metabolism.