Spine
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Retrospective case-control. ⋯ Postoperative infection after the surgical treatment of idiopathic scoliosis can successfully be treated with irrigation and debridement, instrumentation removal, and a course of antibiotics. Although less curve correction was achieved in the infected group, there were no differences in patient-reported outcomes when compared with the noninfected group.
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The effects of a low, local dose of a tumor necrosis factor-alpha (TNF-alpha) inhibitor on neuropathic pain behaviors in a rat chronic constriction injury model were evaluated. ⋯ This preclinical study indicates that delivering TNF-alpha inhibitors by means of a locally administered polymeric formulation provides long-lasting analgesia in an inflammatory neuropathic pain model.
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Review Meta Analysis Comparative Study
Examining heterogeneity in meta-analysis: comparing results of randomized trials and nonrandomized studies of interventions for low back pain.
Literature review. ⋯ Comparisons between RCTs and NRSs may be influenced by various factors, including study design. However, other factors were more powerful explanatory variables than study design. These factors included pain duration, involvement of workers' compensation, presence of spondylolisthesis, previous surgery, and levels fused.
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Comparative Study Controlled Clinical Trial
Quantitative analysis of back muscle degeneration in the patients with the degenerative lumbar flat back using a digital image analysis: comparison with the normal controls.
The degree of back muscle degeneration was quantified in patients with a degenerative lumbar flat back and a normal control group by magnetic resonance (MR) imaging and a digital image analysis technique. ⋯ T2 weighted MR Image analysis of the paravertebral back muscles in patients with degenerative lumbar flat back showed significant fat infiltration compared with those in the normal control using digital image analysis. Digital image analysis of the paravertebral back muscles is a useful tool for measuring the degree of paravertebral back muscle degeneration.
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Randomized Controlled Trial Comparative Study
Self-report measures best explain changes in disability compared with physical measures after exercise rehabilitation for chronic low back pain.
Sixteen-week intervention for chronic patients with low back pain (LBP) with 9-month follow-up. Primary randomization at 4 weeks into either supervised Swiss ball exercise or an exercise advice group. ⋯ Supervised exercise is a more successful subsequent to manual treatment compared with exercise advice. The improvements associated with this type of program were primarily manifested in the psychologic self-report measures rather than physical measurements.