Spine
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Multicenter Study Comparative Study
Age-gender matched comparison of SRS instrument scores between adult deformity and normal adults: are all SRS domains disease specific?
Prospective, observational study. ⋯ Our findings confirm the SRS instrument has excellent discriminate validity in the adult population. It appears to be disease-specific in the domains of pain, appearance and activity in adult spinal deformity patients who have not had prior surgery.
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Multicenter Study
Predicting outcome and complications in the surgical treatment of adult scoliosis.
prospective, multicenter. ⋯ By applying the classification of adult deformity and considering baseline health status, models for predicting outcome can be established. Further work will refine these models and permit clinical validation. This effort will help establish reliable clinical models such that treatment algorithms can be established for the challenging patients suffering from adult spinal deformity.
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Randomized Controlled Trial
Physical therapy treatment of back complaints on children and adolescents.
A randomized controlled trial was performed. ⋯ An individual assessment by a knowledgeable physiotherapist and an active treatment model improve how children and adolescents experience their back problems with respect to health and physical function, pain, strength, and mobility, regardless of whether treatment consists of a home exercise program with follow-up or home exercise combined with exercise and treatment supervised by a physiotherapist.
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Comparative Study Clinical Trial
Bone morphogenetic protein (RhBMP-2) as a substitute for iliac crest bone graft in multilevel adult spinal deformity surgery: minimum two-year evaluation of fusion.
Prospective, single center, nonblinded radiographic analysis of anterior and posterior adult spinal deformity fusions performed with bone morphogenetic protein (rhBMP-2). ⋯ In multilevel ASF, BMP (10 mg/level) generates fusion without autogenous bone. In multilevel PSF, BMP (20 mg/level) with LBG and TCP-HA produced fusion. BMP (40 mg/level) and TCP-HA without LBG achieved fusion. In multilevel spinal fusion, rhBMP-2 eliminated the necessity for iliac crest bone graft and yielded an excellent fusion rate.
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Comparative Study
Anterior spinal fusion versus posterior spinal fusion for moderate lumbar/thoracolumbar adolescent idiopathic scoliosis: a prospective study.
A prospective study. ⋯ ASF versus PSF comparison in treating moderate lumbar/thoracolumbar AIS did not show significant differences in regards to safety or efficacy but demonstrated shorter fusion levels, reduced surgical trauma and costs in ASF.