Spine
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Cerebral activation by lumbar mechanical stimulus was investigated by functional magnetic resonance imaging in healthy subjects and patients with chronic low back pain (LBP). ⋯ Chronic LBP patients showed increased tenderness at the lower back, higher aversive reaction to pain, and augmented LBP-related cerebral activation. The LBP-related activation is characterized by the absence of sensory-discriminative component and the involvement of PCC.
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Biomechanical study using human cadaver spines. ⋯ Cervical TDR at 2 levels can provide near-normal mobility at both levels without destabilizing the implanted segments or affecting adjacent segment motions. These observations lend support to the notion that single or multilevel cervical TDR may be advantageous when compared to fusion.
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Experimental study. ⋯ The biomechanical stability of the same size screws inserted at the expanded and nonexpanded pedicles are the same after 3 months. Even dilation of the pedicle decreases the pullout strength of the screw at the beginning, and the pull out strength of both sides became equal after 3 months. The remodeling capacity of pedicles and overgrowth of bone on screws may have an effect on this result.
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Narrative review. ⋯ Key opinion leaders using the GRADE System made treatment recommendations based on systematically reviewed evidence, blended with clinical expertise and patient preference on critical, controversial questions in spine oncology.