Spine
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The authors investigated gait abnormalities and mechanical hypersensitivity associated with invertebral disc herniation in a rat model of radiculopathy. Further evaluation involved assessing how nucleus pulposus (NP) injury affected systemic cytokine expression and molecular changes at the dorsal root ganglion (DRG). ⋯ This model of radiculopathy provides evidence of altered gait in a model of noncompressive disc herniation. Systemic inflammation was absent, but mechanical allodynia, local inflammation, and autoreactive immune activation were observed. Future work will involve therapeutic interventions to rescue animals from the phenotype of inflammatory radiculopathy.
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Pedicle involvement in spinal tuberculosis (TB), the prevertebral abscess formation, severity of vertebral body, and disc collapse were evaluated from magnetic resonance imaging (MRI) of the patients. ⋯ The posterior spinal element, specifically the pedicle is not uncommonly involved in spinal TB. Pedicle involvement is part of the disease process and usually associated with relatively severe vertebral body and disc destruction, wide prevertebral abscess, and severe kyphosis. Pedicle involvement can be detected early from MRI and need to be documented as it may influence the treatment strategy.
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A retrospective investigation of clinical and radiologic outcomes after surgical treatment for 2-level cervical spondylotic myelopathy (CSM). ⋯ Surgical managements of 2-level CSM using ACDF or ACCF were found to be similar in terms of clinical outcomes. However, 2-level ACDF was found to be superior to 1-level ACCF in terms of operation times, bleeding amounts, and radiologic results.
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Case Reports
Metastatic carcinoma related long segment thoracic spinal epidural hematoma: a case report.
Case report. ⋯ Spinal epidural hematoma can occur in association with metastatic tumors in that area.