Spine
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Randomized Controlled Trial
Effect of epsilon aminocaproic acid on red-cell transfusion requirements in major spinal surgery.
: Randomized, placebo-controlled trial. ⋯ : The difference in total allogeneic RBC transfusions between the groups was not statistically significant. EACA was associated with a 30% (0.8 units) reduction in postoperative RBC transfusions and a 1-day reduction in ICU LOS, without an increased incidence of thromboembolic events. EACA may be considered for patients undergoing major spinal surgery. Larger studies are needed to evaluate the relationship between EACA and total RBC requirements.
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Comparative Study
Trends in health care expenditures, utilization, and health status among US adults with spine problems, 1997-2006.
Analysis of nationally representative survey data for spine-related health care expenditures, utilization and self-reported health status. ⋯ Expenditure increases for spine-related inpatient, prescription, and emergency services were primarily the result of increasing per-user expenditures, while those related to outpatient visits were primarily due to an increase in the number of users of ambulatory services.
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Comparative Study
Development of the Italian version of the Oswestry Disability Index (ODI-I): A cross-cultural adaptation, reliability, and validity study.
Evaluation of the psychometric properties of a translated, culturally adapted questionnaire. ⋯ The ODI outcome measure was successfully translated into Italian, showing good factorial structure and psychometric properties, replicating the results of existing language versions of the questionnaire. Its use is recommended in research practice.
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Randomized Controlled Trial Multicenter Study Comparative Study
Sagittal cervical alignment after cervical disc arthroplasty and anterior cervical discectomy and fusion: results of a prospective, randomized, controlled trial.
Radiographic results of a multicenter, prospective randomized study comparing 1-level cervical total disc replacement (TDR-C) with anterior cervical discectomy and fusion (ACDF). ⋯ In both TDR-C and ACDF, lordosis increased at the device-level, cranial adjacent level, and in total cervical lordosis, while lordosis decreased at the caudal adjacent level. Although ACDF facilitated a greater increase in device level lordosis (+1.25 degrees ) and less loss of lordosis at the caudal adjacent level compared with TDR-C (-0.39 degrees ), the clinical relevance of the small differences remain unknown.