Spine
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Randomized Controlled Trial
Effect of epsilon aminocaproic acid on red-cell transfusion requirements in major spinal surgery.
: Randomized, placebo-controlled trial. ⋯ : The difference in total allogeneic RBC transfusions between the groups was not statistically significant. EACA was associated with a 30% (0.8 units) reduction in postoperative RBC transfusions and a 1-day reduction in ICU LOS, without an increased incidence of thromboembolic events. EACA may be considered for patients undergoing major spinal surgery. Larger studies are needed to evaluate the relationship between EACA and total RBC requirements.
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Comparative Study
Trends in health care expenditures, utilization, and health status among US adults with spine problems, 1997-2006.
Analysis of nationally representative survey data for spine-related health care expenditures, utilization and self-reported health status. ⋯ Expenditure increases for spine-related inpatient, prescription, and emergency services were primarily the result of increasing per-user expenditures, while those related to outpatient visits were primarily due to an increase in the number of users of ambulatory services.
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Prospective cohort study. ⋯ Larger anular defects and less disc removal increased the risk of reherniation. Greater volumes of disc removal were associated with accelerated disc height loss. In the setting of larger anular defects or less aggressive disc removal, concern for recurrent herniation should be increased during outpatient follow-up. In this situation effective anular repair may be helpful.
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Comparative Study
Development of the Italian version of the Oswestry Disability Index (ODI-I): A cross-cultural adaptation, reliability, and validity study.
Evaluation of the psychometric properties of a translated, culturally adapted questionnaire. ⋯ The ODI outcome measure was successfully translated into Italian, showing good factorial structure and psychometric properties, replicating the results of existing language versions of the questionnaire. Its use is recommended in research practice.
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Cross-sectional cohort. ⋯ This regression-based algorithm may be used to predict SF-6D scores in studies of lumbar degenerative disease that have collected ODI but not utility scores.