Spine
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A retrospective review of data prospectively entered into a multicenter database. ⋯ The introduction of this system has led to a reduction in the variation of treatment approaches; however, our data suggest that 6% to 29% of the time, depending on the curve pattern, there are other aspects of the clinical and radiographic deformity that suggest deviation from the recommendations of the classification system. The outcome of adherence to this system remains yet to be evaluated.
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Retrospective study. ⋯ In Lenke 1A type scoliosis, the selection of LIV is highly correlated with the presence of adding-on; incidence increases dramatically when the preoperative LIV+1 deviation from CSVL is more than 10 mm. Choosing DV (the first vertebra in cephalad direction from sacrum with deviation from CSVL of more than 10 mm) as LIV may provide the best outcome as it not only prevents adding-on but also conserves more lumbar motion.
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A prevalence and reliability study of Modic changes (MCs) in the cervical spine. ⋯ A high prevalence of MCs was observed with type 2 predominating. The C5/6 and C6/7 levels are most effected. Patients with MC are more likely to have a DH at the same level. MC type 2 predominates. The classification is reliable.
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Vertebral growth plates at different postnatal ages were assessed for active intercellular signaling pathways. ⋯ During growth and differentiation of the vertebral growth plate, its different components respond at different times to different intercellular signaling ligands. Response to most of these signals is dramatically downregulated at the end of vertebral growth.
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Review Meta Analysis
Spinal manipulative therapy for chronic low-back pain: an update of a Cochrane review.
Systematic review of interventions. ⋯ High-quality evidence suggests that there is no clinically relevant difference between SMT and other interventions for reducing pain and improving function in patients with chronic low-back pain. Determining cost-effectiveness of care has high priority.