Spine
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Comparative biomechanical study was conducted in osteoporotic human cadaveric spines. ⋯ Significant increases in pullout strength can be accomplished by injecting a limited quantity of bone cement through a fenestrated screw while minimizing the risks associated with higher volume. The majority of implants were removed without damaging the vertebra as the bone cement sheared off at the fenestrations.
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The study aims to investigate the dimensions and angular orientations of the pedicles of the first sacral segment at the L5-S1 junctions affected by transitional variations. ⋯ S1 pedicle morphology and angulation in the first sacral segment are different from the normal in L5-S1 transitional situations and hence should be mapped accordingly in screw placements at the region in context of such common variations.
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A posterolateral lumbar fusion model in osteoporotic rats. OBJECTIVE.: To assess the effect of alendronate on spine fusion in an osteoporotic animal model. ⋯ Alendronate was effective for radiologic, biomechanical, and histologic success of spine fusion in an osteoporotic animal model. Though much of the graft bone was not resorbed, alendronate increased biomechanical strength with ingrowth of new bone formation in osteoporotic animals. This study suggests the alendronate may improve spine fusion healing in the presence of osteoporosis.
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Comparative Study
Reverse causality in the association between whiplash and symptoms of anxiety and depression: the HUNT study.
Longitudinal population-based cohort study. ⋯ This is the first published study with a prewhiplash prospective evaluation of psychological status. Our findings are in conflict with previous research suggesting whiplash to be the cause of associated psychological symptoms rather than their consequence. Self-reported whiplash injury was clinically relevant as it independently increased subsequent disability pension award. The strength of this effect, even in the absence of neck pain, suggests the ascertainment of this diagnostic label, or factors associated with this, are important predictors of disability.