Spine
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Basic pain study using osteoporotic rodent models. ⋯ N/A.
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Randomized Controlled Trial Multicenter Study
Randomized, double-blind, placebo-controlled, trial of transforaminal epidural etanercept for the treatment of symptomatic lumbar disc herniation.
Multicenter, randomized, double-blind, placebo-controlled trial. ⋯ Two transforaminal injections of etanercept provided clinically significant reductions in mean daily WLP and worst back pain compared with placebo for subjects with symptomatic LDH. Epidural etanercept may offer patients with sciatica a safe and effective nonoperative treatment.
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Randomized Controlled Trial Comparative Study
Effect of facet joint injection versus systemic steroids in low back pain: a randomized controlled trial.
Randomized clinical trial. ⋯ Both treatments were effective, with a slight superiority of the intra-articular injection of steroids over intramuscular injection.
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Comparative Study
Five-year outcomes of minimally invasive versus open transforaminal lumbar interbody fusion: a matched-pair comparison study.
Retrospective analysis of prospectively collected data. ⋯ MIS TLIF is comparable with open TLIF in terms of midterm clinical outcomes and fusion rates with the additional benefits of less initial postoperative pain, less blood loss, earlier rehabilitation, and shorter hospitalization.