Spine
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Randomized Controlled Trial Multicenter Study
rhBMP-2 for posterolateral instrumented lumbar fusion: a multicenter prospective randomized controlled trial.
Multicenter randomized controlled trial. ⋯ The use of rhBMP-2 for instrumented posterolateral lumbar surgery significantly improves the chances of radiographical fusion compared with the use of autograft. However, there is no associated improvement in clinical outcome within a 4-year follow-up period. These results suggest that use of rhBMP-2 should be considered in cases where lumbar arthrodesis is of primary concern.
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Review Case Reports
Cluster phenomenon of vertebral refractures after percutaneous vertebroplasty in a patient with glucocorticosteroid-induced osteoporosis: case report and review of the literature.
A case report and literature review. ⋯ The use of PVP as a therapeutic alternative for the treatment of VCFs in patients with GIOP is still controversial. As seen in our case, even when the management decisions were made in consideration of the patient's pulmonary infection, the outcome was disastrous with the cluster phenomenon of vertebral refractures. Current findings suggest a compelling need for high-quality studies investigating cement augmentation procedures in patients with VCF with GIOP.
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Systematic review. ⋯ There is strong evidence that submaximal capacity can be detected in patients with chronic low back pain with a lumbar motion monitor or visual observations accompanying a functional capacity evaluation lifting test.
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Comparative Study
Comparison of perioperative outcomes and cost of spinal fusion for cervical trauma: weekday versus weekend admissions.
Retrospective database analysis. ⋯ The weekend cohorts in all surgical approaches incurred a greater length of stay and total hospital costs than their weekday counterparts. The ACF-treated weekend cohort demonstrated significantly greater incidences of postoperative infection, cardiac complications, and urinary tract infection. There were no significant differences in mortality based on the admission day for any surgical approach. Further research is warranted to further evaluate hospital utilization, costs, and patient outcomes based on the admission day.
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Animal study. ⋯ This finding provides a possible neuroanatomical explanation for referred pain in the ASIC from vertebral bodies.