Spine
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Multicenter Study
No relationship between body mass index and changes in pain and disability after exercise rehabilitation for patients with mild to moderate chronic low back pain.
A retrospective multicenter study. ⋯ There was no significant relationship between BMI and self-reported pain and disability in cLBP participants. BMI was not a predictor of exercise-induced changes in pain and disability. The reliance on BMI as a sole measurement of obesity in cLBP research may be unwarranted.
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Randomized Controlled Trial
Natural history and risk factors for adjacent vertebral fractures in the fracture intervention trial.
Retrospective analysis of prospectively collected follow-up data for 2.9 years. ⋯ New vertebral fractures adjacent to prevalent fractures occurred relatively infrequently in this treatment trial of alendronate in females with osteoporosis, and were more common with older age at randomization, lower bone mineral density and placebo treatment.
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Multicenter Study
Complications in pediatric spine surgery using the vertical expandable prosthetic titanium rib: the French experience.
Multicenter retrospective study of 54 children. ⋯ The complication rate is consistent with that reported in the literature. Correct determination of the levels to be instrumented, preoperative improvement of nutritional status, and better evaluation of the preoperative and postoperative respiratory function are important factors in minimizing the potential complications of a technique that is used in weak patients with complex deformities.
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Prospective review of registry data at a single institution from October 2010 to June 2012. ⋯ Depression and anxiety as assessed by ZDS and MSPQ scores were significantly associated with increased preoperative narcotic use, underscoring the importance of thorough psychological and substance use evaluation in patients being evaluated for spine surgery.
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The histological comparative study was performed on chordoma and notochordal cell rests (NCRs). ⋯ Our study results supported histological similarity and homology of NCRs coexisting in chordoma and in fetal nucleus pulposus. Brachyury activation probably takes an important role in chordoma tumoregenesis.