Spine
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Multicenter Study
Complications after 147 consecutive vertebral column resections for severe pediatric spinal deformity: a multicenter analysis.
Retrospective multicenter review. ⋯ A total of 147 consecutive pediatric VCRs performed by 7 surgeons demonstrated excellent radiographical correction. However, these complex reconstructions were associated with a 59% complication rate, thus emphasizing the challenging nature of these patients and procedures.
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Comparative Study
Cyclic-RGD is as effective as rhBMP-2 in anterior interbody fusion of the sheep cervical spine.
Radiological and histological assessment of fusion status after anterior cervical discectomy and fusion (ACDF) procedure in a sheep spinal fusion model. ⋯ In this animal model the combination of cRGD and a mineralized collagen matrix showed superior fusion results in comparison with the mineralized collagen alone. Further, cRGD was comparably effective to rhBMP-2 in promoting interbody fusion by demonstrating less ectopic bone formations.
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Review Meta Analysis Comparative Study
Mid- to long-term outcomes in adolescent idiopathic scoliosis after instrumented posterior spinal fusion: a meta-analysis.
Meta-analysis on mid- to long-term outcomes in adolescent idiopathic scoliosis after instrumented posterior spinal fusion. ⋯ This study confirms the negative effect of Harrington rods on sagittal alignment. We further found that the degree of correction in the coronal and sagittal planes was higher after Cotrel-Dubousset instrumentation than all-pedicle screw fixation. All-pedicle screw constructs offered the lower risk of mid- to long-term complications and revision surgery.
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Review Case Reports
Diagnosis and treatment of Fusobacterium nucleatum discitis and vertebral osteomyelitis: case report and review of the literature.
Case report. ⋯ We report a rare case of Fusobacterium vertebral osteomyelitis. This condition is associated with several comorbid and concomitant conditions including gastrointestinal complications. Effective treatment includes thoracolumbar orthosis bracing and intravenous antibiotic therapy.
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Prospective population-based cohort study. ⋯ One-fourth of the workers who received work disability compensation for a back injury self-reported reinjury after returning to work. Baseline variables in multiple domains predicted occupational back reinjury. Increased knowledge of early risk factors for reinjury may help to lead to interventions, such as efforts to reduce fear avoidance and graded activity to promote recovery, effective in lowering the risk of reinjury.