Spine
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Observational Study
Preoperative magnetic resonance imaging is associated with baseline neurological status and can predict postoperative recovery in patients with cervical spondylotic myelopathy.
A blinded observational study of consecutive patients, prospectively enrolled and followed up to 1 year postoperatively. ⋯ 2.
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Retrospective comparative study using prospectively collected data. ⋯ 2.
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Cross-sectional, questionnaire study. ⋯ Findings highlight extreme variability in practice associated with a notable lack of standard of care and provide a baseline for utility studies that may lead to more evidence-driven care.
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The possibility to prevent acute spinal cord injury (ASCI) by selective infliximab combined with methylprednisolone (MP) was assessed in experimental ASCI. ⋯ Infliximab combined with methylprednisolone may be an effective treatment for the recovery of ASCI. Further study is needed to determine if this neuroprotective effect is seen for long-term outcomes especially in human ASCI.