Spine
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Observational Study
Transient low back pain development during standing predicts future clinical low back pain in previously asymptomatic individuals.
Longitudinal, observational. ⋯ Transient LBP development during prolonged standing is a positive predictive factor for future clinical LBP in previously asymptomatic individuals. Individuals who experience transient LBP during standing may be considered a "preclinical" group who are at increased risk for future LBP disorders.
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Animal study. ⋯ Our results indicate that nerve compression plus NP application produces the most pain-related behavior. CGRP-IR nerve terminals increased in laminae I and II that transmit pain and in laminae III to VI that transmit proprioception. Findings suggest that nerve compression plus NP application induces changes in CGRP expression in the superficial and deep laminae, and these changes are partly responsible for disc herniation pain.
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Multicenter Study
Responsiveness and interpretability of the Portuguese version of the Quebec Back Pain Disability Scale in patients with chronic low back pain.
A prospective cohort study with a 6-week follow-up of patients with chronic low back pain undergoing physiotherapy. ⋯ N/A.
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Validity and responsiveness study using a randomized clinical trial and prospective cohort study of patients with low back pain (LBP). ⋯ 2.
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A posterolateral rabbit spinal fusion model was used to evaluate the effects of recombinant human bone morphogenetic protein-2 (rhBMP-2) and teriparatide (PTH [1-34]) used individually and in combination on spinal fusion outcomes. ⋯ N/A.