Spine
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This was a subanalysis of an international, multicenter, open-label study. ⋯ Results from the analysis suggest that denosumab is potentially effective treatment for patients with GCTB of the spine including the sacrum. The adverse event profile was consistent with the full study population.Level of Evidence: 2.
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Retrospective cohort study. ⋯ The overall outcome of physical well-being improvement is decided within 3 months postoperatively, in proportion to the recovery in myelopathy, with a relatively high chance of meaningful improvement over the next 21 months. The outcome of improvement in mental well-being is decided within 3 months postoperatively, independently from the recovery in myelopathy, with a low chance of meaningful improvement over the next 21 months.Level of Evidence: 3.
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Construct validity and reliability of the Japanese Version of the Lumbar Stiffness Disability Index.
Outcome study to determine the construct validity and reliability of the Japanese version of the Lumbar Stiffness Disability Index. ⋯ The construct validity and reliability of the Japanese version of the LSDI were confirmed. The J-LSDI can be used to evaluate lumbar stiffness and associated disability in Japanese patients following lumbar spinal surgery.Level of Evidence: 2.