Spine
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Assessment of bone formation in an ovine interbody fusion study. ⋯ We have demonstrated the preclinical safety and efficacy of OsteoAdapt SP in a clinically relevant large animal model, supporting faster and more robust new bone formation within the interbody cage, comparable to or better than the gold standard, ICBG, in all measures.
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Comparative Study
Comparison of Bone Mineral Density in Children and Adolescents on CT Versus DEXA Scan.
Retrospective cross-sectional. ⋯ HU on lumbar CT in children and adolescents with DEXA Z -scores <-2.0, were lower when compared with healthy matched controls. This study suggests that HU on opportunistic CT scans of the spine may be used as a reasonable proxy for BMD in the pediatric population.
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Comparative Study Observational Study
Comparison of Patients Operated for Lumbar Spinal Stenosis with and without Spondylolisthesis - A Secondary Analysis of the NORDSTEN Trials.
Observational cohort study (secondary analysis of two randomized trials). ⋯ II.
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Retrospective cohort study. ⋯ L1PA may be a helpful radiographic consideration that translates to clinically relevant outcomes in spinal deformity. However, it does not appear as predictive of patient outcomes after single-level fusion for patients with L4-L5 degenerative spondylolisthesis. Further studies are warranted to investigate the role of L1PA in degenerative spine patients.
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Retrospective analysis of prospectively collected data. ⋯ Level II.