Spine
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An in vitro study to investigate the effect of pressure stimulation on nucleus pulposus (NP) cells. ⋯ The results link mechanotransduction to the downstream ECM protein synthesis and suggest slow exercises that correspond with spontaneous calcium oscillations in NP cells can be effective to stimulate ECM synthesis in IVD.
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Multicenter Study
Rates of Loosening, Failure, and Revision of Iliac Fixation in Adult Deformity Surgery.
Retrospective cohort review of a prospective multicenter database. ⋯ Lumbopelvic fixation failure rates were high following ASD correction, and associated with lesser clinical improvements. S2AI screws were more likely to demonstrate loosening, but less commonly associated with rod fractures at the lumbopelvic region.
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A prospective, multicenter study. ⋯ Tc-MEP alert during position change is an important sign of spinal cord injury due to alignment change at the upper thoracic spine. Tc-MEP monitoring before supine-to-prone position change was necessary to prevent spinal cord injury in surgeries for T-OPLL.