Spine
-
Randomized Controlled Trial Multicenter Study Comparative Study
Efficacy of Biphasic Calcium Phosphate Ceramic With a Needle-shaped Surface Topography Versus Autograft in Instrumented Posterolateral Spinal Fusion: A Randomized Trial.
A multicenter randomized controlled noninferiority trial with intrapatient comparisons. ⋯ This clinical trial demonstrates noninferiority and indicates superiority of MagnetOs Granules as a standalone ceramic when compared to autograft for posterolateral spinal fusion. These results challange the belief that autologous bone is the most optimal graft material.
-
Multicenter Study
Imaging Characteristics of Non-Rheumatoid Arthritis Patients With Retro-Odontoid Pseudotumor: A Multicenter Case-Control Study.
Multicenter case-control study. ⋯ The development of ROP was associated with degeneration of facet joints and intervertebral disks in the middle and lower cervical spine. Our findings suggest that decreased mobility of the middle and lower cervical spine may cause instability in the upper cervical spine, leading to the formation of ROP.
-
Comparative Study
Comparison of Bone Mineral Density in Children and Adolescents on CT Versus DEXA Scan.
Retrospective cross-sectional. ⋯ HU on lumbar CT in children and adolescents with DEXA Z -scores <-2.0, were lower when compared with healthy matched controls. This study suggests that HU on opportunistic CT scans of the spine may be used as a reasonable proxy for BMD in the pediatric population.
-
Assessment of bone formation in an ovine interbody fusion study. ⋯ We have demonstrated the preclinical safety and efficacy of OsteoAdapt SP in a clinically relevant large animal model, supporting faster and more robust new bone formation within the interbody cage, comparable to or better than the gold standard, ICBG, in all measures.
-
Comparative Study Observational Study
Comparison of Patients Operated for Lumbar Spinal Stenosis with and without Spondylolisthesis - A Secondary Analysis of the NORDSTEN Trials.
Observational cohort study (secondary analysis of two randomized trials). ⋯ II.