Ear, nose, & throat journal
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Review Case Reports
Giant cell reparative granuloma presenting as a midline nasal mass.
Giant cell reparative granuloma (GCRG) is an uncommon entity that has been reported in all areas of the head and neck. It must be distinguished from true giant cell tumors, brown tumors of hyperparathyroidism, aneurysmal bone cysts, and fibrous dysplasia. It responds well to surgical debulking and curettage and has a benign clinical course. We describe a case report of a GCRG presenting as a midline nasal mass and review the pertinent English language literature.
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EMEC is a clear-cell tumor of salivary gland origin. Since it was first recognized as a distinct salivary gland malignancy in 1956, sporadic cases have been reported. A case of an EMEC in a parotid gland of a 77-year-old man is described. The clinical and histopathologic features of this unusual neoplasm, as well as a description of the immunohistochemistry and current management of this uncommon entity are presented.
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Case Reports
Midfacial necrotizing lesion of the nasal cavity attributable to peripheral T-cell lymphoma.
The initial progression of a nonhealing ulcerative lesion in the nasopalatal region with nondiagnostic biopsy results, combined with progression of systemic symptoms, is suggestive of a PTL. Because therapy requires accurate histologic diagnosis, the clinician must be persistent to make a correct diagnosis. As the disease progresses, PTL histology matures, allowing diagnosis with immunohistochemical techniques. It is possible that earlier diagnosis will allow more timely treatment and a reduction in mortality related to this disease.
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Noma and noma neonatorum are rare gangrenous diseases that result in mutilating loss of tissue in the oronasal region. Noma usually occurs in patients between the ages of 2 and 5 years who are malnourished, have suffered a precedent illness, or are in some way immunodeficient, or all of the above. The gangrenous slough is thought to be caused by a mixed infection of oral bacterial pathogens. ⋯ Both diseases are rare in North America. Patients with noma and noma neonatorum were treated at the Children's Hospital and Medical Center, Seattle, WA. We present these cases and a literature review.