Journal of computer assisted tomography
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J Comput Assist Tomogr · May 2010
Differential changes in deep and cortical gray matters of patients with multiple sclerosis: a quantitative magnetic resonance imaging study.
The objective of our study was to evaluate the changes in quantitative diffusion tensor (DT) metrics and normalized T2-signal intensity (nT2-SI) values of normal-appearing cortical gray matter (CGM) and deep gray matter (DGM) in patients with multiple sclerosis (MS). ⋯ In CGM, the change in quantitative DT metrics of MS patients and the association with BPF and T2 LVs suggest the existence of microstructural destruction corresponding to inflammation, demyelination, or wallerian degeneration, but the changes in CGM were independent of the concomitant changes in BPF and T2 lesion. In DGM, a decrease of nT2-SI in MS patients and the correlation of nT2-SI values with BPF (brain atrophy) suggest excessive iron deposition related to chronic destruction. Our investigation indicates the possibility of different mechanism of pathological change in CGM and DGM.
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J Comput Assist Tomogr · May 2010
The value of the apparent diffusion coefficient in differentiating stage IA endometrial carcinoma from normal endometrium and benign diseases of the endometrium: initial study at 3-T magnetic resonance scanner.
To retrospectively assess the feasibility of diffusion-weighted (DW) magnetic resonance (MR) imaging of stage IA endometrial carcinoma and to investigate whether the apparent diffusion coefficient (ADC) values of stage IA endometrial carcinoma differ from those of normal endometrium and benign diseases of the endometrium. ⋯ The measurements of the ADC values have the potential to quantitatively differentiate stage IA endometrial carcinoma from normal endometrium and benign diseases of the endometrium. We propose adding DW imaging as an adjunct sequence in the routine MR protocol for the assessment of uterine lesions.
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J Comput Assist Tomogr · May 2010
Comparative StudyComparison of computed tomography angiography with digital subtraction angiography in the assessment of clipped intracranial aneurysms.
To examine whether computed tomography angiography (CTA) is comparable to digital subtraction angiography (DSA) in assessing clipped intracranial aneurysms. ⋯ Computed tomography angiography has high sensitivity and specificity for residual aneurysm detection and parent vessel occlusion. It is not accurate in neck remnant detection, although these were small and of uncertain clinical significance. This suggests that CTA is useful for follow-up of clipped aneurysms. However, given the potential to miss neck remnants or small residual aneurysms, it is recommended to perform initial DSA and CTA to select cases in which CTA follow-up is appropriate.
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J Comput Assist Tomogr · May 2010
Relationship between liver function and liver signal intensity in hepatobiliary phase of gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging.
To evaluate the effect of liver function on liver signal intensity in gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging in humans and to examine the biochemical factors related to signal intensity in the hepatobiliary phase. ⋯ The degree of liver enhancement in the hepatobiliary phase may reflect liver cell function. The measurement of liver signal intensity in the hepatobiliary phase may be useful in predicting whole and regional hepatic functional reserves.
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J Comput Assist Tomogr · Mar 2010
Comparative StudyIsotropic 3-dimensional fast spin echo imaging versus standard 2-dimensional imaging at 3.0 T of the knee: artificial cartilage and meniscal lesions in a porcine model.
To compare different fat-saturated (FS) 3-dimensional (3D) intermediate-weighted (IM-w) fast spin echo (FSE) sequences with a standard FS 2-dimensional (2D) IM-w FSE sequence using a porcine in vitro model with artificially created cartilage and meniscus lesions. ⋯ Although the 3D FSE sequence performed better in depiction and characterization of cartilage abnormalities than the standard 2D FSE sequence, we currently do not recommend to use it as substitute. For the diagnosis of meniscal defects, however, no significant improvement was found.