Intensive care medicine
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Intensive care medicine · Feb 1996
Comparative Study Retracted PublicationCirculating adhesion molecules in the critically ill: a comparison between trauma and sepsis patients.
The time course of circulating adhesion molecules was monitored in traumatized and sepsis patients. ⋯ Endothelial damage may result in multiple-organ dysfunction syndrome. Adhesion molecules are considered to be a cornerstone in this process. Trauma patients showed lower plasma levels of circulating adhesion molecules than did sepsis patients indicating more pronounced (inflammatory related) endothelial activation or damage in sepsis. Therapeutic modulation of circulating adhesion molecules may be of benefit to the patients outcome and therefore warrants further study.