Intensive care medicine
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Intensive care medicine · Jan 2007
Randomized Controlled TrialDanger of helmet continuous positive airway pressure during failure of fresh gas source supply.
To assess the behavior of different helmets after discontinuation of fresh gas flow by disconnection at the helmet inlet, flow generator, or gas source. ⋯ While the use of a safety valve proved effective in limiting CO2 rebreathing, it did not protect from the risk of hypoxia related to decrease in FIO2 and loss of PEEP. In addition to a safety antisuffocation valve, a dedicated monitoring and alarming systems are needed to employ helmet CPAP safely.
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Intensive care medicine · Jan 2007
Comparative StudyEntropy is more resistant to artifacts than bispectral index in brain-dead organ donors.
To evaluate the usefulness of entropy and the bispectral index (BIS) in brain-dead subjects. ⋯ Both entropy and BIS showed nonzero values due to artifacts after brain death diagnosis. BIS was more liable to artifacts than entropy. Neither of these indices are diagnostic tools, and care should be taken when interpreting EEG and EEG-derived indices in the evaluation of brain death.
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Intensive care medicine · Jan 2007
Decrease in circulating dendritic cells predicts fatal outcome in septic shock.
Biomarkers allowing accurate early staging of septic shock patients are lacking despite their obvious interest for patient management. Experimental models of septic shock in mouse previously noted a decrease in dendritic cell numbers. The aim of the study was to find a rapid reproducible biological test for an assessment of disease severity. ⋯ The monitoring of blood dendritic cell count may provide an early and valuable assessment of the severity of the host response against infection and may influence the therapeutic management of septic shock patients.
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Intensive care medicine · Jan 2007
Postresuscitation myocardial dysfunction: correlated factors and prognostic implications.
To evaluate the clinical factors correlated with postresuscitation myocardial dysfunction and the prognostic implication such dysfunction may have. ⋯ Postresuscitation left ventricular dysfunction is correlated with a number of clinical factors, among which past history of myocardial infarction, epinephrine dose, and the cause of cardiac arrest play independent roles. Meanwhile, IVRT 100 ms or longer 6 h postresuscitation predicts poor survival outcomes and serves as a marker of poor prognosis.