Intensive care medicine
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Intensive care medicine · Aug 2015
Early fluid accumulation in children with shock and ICU mortality: a matched case-control study.
The purpose of this study was to evaluate the association between early fluid accumulation and mortality in children with shock states. ⋯ The presence, severity and duration of early fluid are associated with increased ICU mortality in children admitted to the pediatric ICU in shock states.
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Intensive care medicine · Aug 2015
Observational Studyβ-D-Glucan and Candida albicans germ tube antibody in ICU patients with invasive candidiasis.
To assess the performance of (1→3)-β-D-glucan (BDG) and Candida albicans germ tube antibody (CAGTA) for the diagnosis of invasive candidiasis (IC) in a prospective cohort of 107 unselected, non-neutropenic ICU patients. ⋯ Two consecutive BDG levels ≥80 pg/mL allowed discrimination among IC and high-grade colonization. Systemic antifungal therapy could not be monitored with biomarker kinetics, and BDG levels were not subject to interference by confounding factors in either colonized or infected patients or with low-grade colonization.