Intensive care medicine
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Intensive care medicine · Dec 2020
ReviewProne position in ARDS patients: why, when, how and for whom.
In ARDS patients, the change from supine to prone position generates a more even distribution of the gas-tissue ratios along the dependent-nondependent axis and a more homogeneous distribution of lung stress and strain. The change to prone position is generally accompanied by a marked improvement in arterial blood gases, which is mainly due to a better overall ventilation/perfusion matching. Improvement in oxygenation and reduction in mortality are the main reasons to implement prone position in patients with ARDS. ⋯ The most frequent adverse events are pressure sores and facial edema. Recently, the use of prone position has been extended to non-intubated spontaneously breathing patients affected with COVID-19 ARDS. The effects of this intervention on outcomes are still uncertain.
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Intensive care medicine · Dec 2020
Physiological and quantitative CT-scan characterization of COVID-19 and typical ARDS: a matched cohort study.
To investigate whether COVID-19-ARDS differs from all-cause ARDS. ⋯ COVID-19-ARDS is a subset of ARDS characterized overall by higher compliance and lung gas volume for a given PaO2/FiO2, at least when considered within the timeframe of our study.