Intensive care medicine
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Intensive care medicine · Sep 2020
Observational StudyIncreased mortality in patients with severe SARS-CoV-2 infection admitted within seven days of disease onset.
Coronavirus disease 2019 (COVID-19) is creating an unprecedented healthcare crisis. Understanding the determinants of mortality is crucial to optimise intensive care unit (ICU) resource use and to identify targets for improving survival. ⋯ The excess mortality in patients admitted within a week of disease onset reflected greater non-respiratory severity. Therapeutic interventions against SARS-CoV-2 might impact different clinical endpoints according to time since disease onset.