Intensive care medicine
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Intensive care medicine · Nov 2022
Development of a quality indicator set to measure and improve quality of ICU care in low- and middle-income countries.
To develop a set of actionable quality indicators for critical care suitable for use in low- or middle-income countries (LMICs). ⋯ This consensus exercise provides a common set of indicators to support benchmarking and quality improvement programs for critical care populations in LMICs.
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Intensive care medicine · Nov 2022
Randomized Controlled Trial Multicenter StudyRemote ischemic conditioning in septic shock: the RECO-Sepsis randomized clinical trial.
To determine whether remote ischemic conditioning (RECO), compared to standard care, limits the severity and the consequences of multiple organ failure in patients with septic shock. ⋯ In patients with septic shock, RECO failed to reduce the severity of organ failures assessed by mean daily SOFA score from inclusion to day 4. Adequately powered trials are needed to assess potential delayed benefits of RECO.
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Intensive care medicine · Nov 2022
Meta AnalysisCardiac arrest and complications during non-invasive ventilation: a systematic review and meta-analysis with meta-regression.
The aim of this study was to perform a systematic review and meta-analysis to investigate the incidence rate of cardiac arrest and severe complications occurring under non-invasive ventilation (NIV). ⋯ Cardiac arrest related to NIV occurred in one per 10,000 patients under NIV for ARF treatment. NIV-related cardiac arrest was associated with NIV failure.
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Intensive care medicine · Nov 2022
Randomized Controlled TrialDevelopment and validation of novel sepsis subphenotypes using trajectories of vital signs.
Sepsis is a heterogeneous syndrome and identification of sub-phenotypes is essential. This study used trajectories of vital signs to develop and validate sub-phenotypes and investigated the interaction of sub-phenotypes with treatment using randomized controlled trial data. ⋯ Sepsis sub-phenotypes based on vital sign trajectory were consistent across cohorts, had distinct outcomes, and different responses to treatment with balanced crystalloids versus saline.