Intensive care medicine
-
Intensive care medicine · Nov 2022
Randomized Controlled Trial Multicenter StudyRemote ischemic conditioning in septic shock: the RECO-Sepsis randomized clinical trial.
To determine whether remote ischemic conditioning (RECO), compared to standard care, limits the severity and the consequences of multiple organ failure in patients with septic shock. ⋯ In patients with septic shock, RECO failed to reduce the severity of organ failures assessed by mean daily SOFA score from inclusion to day 4. Adequately powered trials are needed to assess potential delayed benefits of RECO.
-
Intensive care medicine · Nov 2022
Small wards in the ICU: a favorable measure for controlling the transmission of carbapenem-resistant Klebsiella pneumoniae.
Carbapenem-resistant Klebsiella pneumoniae (CRKP) is one of the leading causes of healthcare-associated infections (HAIs) and is particularly pervasive in intensive care units (ICUs). This study takes ICU layout as the research object, and integrates clinical data and bacterial genome analysis to clarify the role of separate, small wards within the ICU in controlling the transmission of CRKP. ⋯ The presence of a long-term hospitalized patient carrying CRKP and positioned in a separate, small ward did not lead to CRKP transmission or infection outbreaks in the ICU. Combining a small-ward ICU layout with normative HAI control measures for multidrug-resistant pathogen infection was effective in reducing CRKP transmission.
-
Intensive care medicine · Nov 2022
Development of a quality indicator set to measure and improve quality of ICU care in low- and middle-income countries.
To develop a set of actionable quality indicators for critical care suitable for use in low- or middle-income countries (LMICs). ⋯ This consensus exercise provides a common set of indicators to support benchmarking and quality improvement programs for critical care populations in LMICs.
-
Intensive care medicine · Nov 2022
Observational StudyExtubation in neurocritical care patients: the ENIO international prospective study.
Neurocritical care patients receive prolonged invasive mechanical ventilation (IMV), but there is poor specific information in this high-risk population about the liberation strategies of invasive mechanical ventilation. ⋯ In neurocritical care patients, extubation failure is high and is associated with unfavourable outcomes. A score could predict extubation success in multiple settings. However, it will be mandatory to validate our findings in another prospective independent cohort.