Intensive care medicine
-
Intensive care medicine · Mar 2001
Effects of combined high-dose partial liquid ventilation and almitrine on pulmonary gas exchange and hemodynamics in an animal model of acute lung injury.
To determine possible additive effects of combined high-dose partial liquid ventilation (PLV) and almitrine bismesylate (ALM) on pulmonary gas exchange and hemodynamics in an animal model of acute lung injury (ALI). ⋯ In an animal model of surfactant depletion induced ALI the combined treatment of PLV and ALM induced no significant improvement in pulmonary gas exchange or hemodynamics when compared to PLV alone. Moreover, high-dose ALM significantly impaired gas exchange and pulmonary hemodynamics.
-
Intensive care medicine · Mar 2001
Comparative StudyAbdomen release in prone position does not improve oxygenation in an experimental model of acute lung injury.
To analyze the effect of abdomen release in the prone position on oxygenation in an experimental model of acute lung injury. ⋯ Abdomen release in prone position does not improve oxygenation in an experimental model of acute lung injury.
-
Intensive care medicine · Mar 2001
Delayed treatment contributes to mortality in ICU patients with severe active pulmonary tuberculosis and acute respiratory failure.
To clarify the patterns of pulmonary tuberculosis (TB) that should result in a high index of suspicion, to increase the chances of early therapy and to identify predictors of 30-day mortality. ⋯ Delayed clinical suspicion and treatment of active pulmonary TB with respiratory failure may contribute to the persistently high mortality rates in ICU patients with these diseases.
-
Intensive care medicine · Mar 2001
Is it feasible to monitor total hepatic blood flow by use of transesophageal echography? An experimental study in pigs.
Total hepatic venous blood flow is determined by the common hepatic arterial blood flow and the venous outflow from stomach, spleen, pancreas, small intestine, and bowel, collected by the portal vein, and thus represents overall splanchnic perfusion. We investigated whether transesophageal echography (TEE) can provide a method for bedside assessment of hepatic venous blood flow useful as a noninvasive method for measuring splanchnic perfusion in clinical practice. ⋯ TEE offers a noninvasive approach for monitoring hepatic perfusion and may be used in patients.
-
Intensive care medicine · Mar 2001
Treatment of ventilation-induced lung injury with exogenous surfactant.
It has been demonstrated that pulmonary surfactant plays a role in the pathophysiology of ventilation-induced lung injury (VILI). Therefore, we investigated whether exogenous surfactant might restore lung function and lung mechanics in an established model of VILI. ⋯ We conclude that exogenous surfactant can be used to treat VILI.