Intensive care medicine
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Intensive care medicine · Jan 2001
Pulmonary administration of prostacyclin (PGI2) during partial liquid ventilation in an oleic acid-induced lung injury: inhalation of aerosol or intratracheal instillation?
The purpose of this study was to investigate the effects of aerosolized prostacyclin (A-PGI2) and intratracheally instilled prostacyclin (I-PGI2) during partial liquid ventilation (PLV) on gas exchange and pulmonary circulation in rabbits with acute respiratory distress. ⋯ The results suggest that both aerosolized and intratracheally instilled PGI2 improve oxygenation and reduce PAP during PLV in oleic acid lung injury.
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Intensive care medicine · Jan 2001
Human errors in a multidisciplinary intensive care unit: a 1-year prospective study.
To determine the incidence and identify risk factors of critical incidents in an ICU. ⋯ Critical incidents add morbidity, workload, and financial burden. A substantial proportion of them are related to human factors with dire consequences. Efforts must focus on timely, appropriate care to avoid planning and execution mishaps at the beginning of the ICU stay; surveillance intensity must be maintained, specially after the fourth day.
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Intensive care medicine · Jan 2001
Chronic obstructive pulmonary disease patients with invasive pulmonary aspergillosis: benefits of intensive care?
Invasive pulmonary aspergillosis (IPA) is increasingly recognized as a cause of acute respiratory failure in patients with chronic obstructive pulmonary disease (COPD) treated with corticosteroids. For these patients admission in intensive care unit (ICU) is often required for life-support and mechanical ventilation. Whether this approach improves outcome is unknown. ⋯ The poor prognosis of intubated COPD patients with IPA, in spite of antifungal treatment suggests that further studies are required to define the limits and indications for ICU management of these patients.
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Intensive care medicine · Jan 2001
Letter Case ReportsLethal heart failure caused by aluminium phosphide poisoning.