Intensive care medicine
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To develop a model able to determine the right time for extubation and to validate its performance. paragraph sign ⋯ VC together with the f/V(T) ratio and MEP offer accurate prediction of early extubation.
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Intensive care medicine · Oct 1999
Clinical Trial Controlled Clinical TrialInfluence of prothrombin complex concentrates on plasma coagulation in critically ill patients.
To evaluate thrombogenicity of prothrombin complex concentrates (PCCs) in critically ill patients. ⋯ Administration of PCCs induces thrombin generation. No evidence for induction of disseminated intravascular coagulation in biochemical terms could be found. When rapid correction of acquired coagulation factor disturbances is warranted, the use of PCCs seems reasonable, but the elevated risk of intravascular thrombus formation should be kept in mind.
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Intensive care medicine · Oct 1999
Review Comparative StudyAssessment of regional tissue oxygenation.
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Intensive care medicine · Oct 1999
Inhaled nitric oxide differentiates pulmonary vasospasm from vascular obstruction after surgery for congenital heart disease.
To evaluate whether a trial of inhaled nitric oxide (NO) differentiates reversible pulmonary vasoconstriction from fixed anatomic obstruction to pulmonary blood flow after surgery for congenital heart disease in patients at risk for pulmonary hypertension. ⋯ A trial of inhaled NO after cardiac surgery in neonates and infants may be useful to differentiate reversible pulmonary vasoconstriction from fixed anatomic obstruction and may provide useful information if temporary support with extracorporeal membrane oxygenation is considered. Failure to respond to inhaled NO should prompt further investigations to rule out a residual obstruction.
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To examine the effect of high levels of pre-intensive care unit (ICU) discharge care, as assessed by the Therapeutic Intervention Scoring System (TISS), on subsequent hospital mortality. ⋯ In a hospital without HDU facilities, patients who are receiving HDU levels of care on discharge from the ICU have a high in-hospital mortality.