Intensive care medicine
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Intensive care medicine · Nov 1996
Thrombolysis using plasminogen activator and heparin reduces cerebral no-reflow after resuscitation from cardiac arrest: an experimental study in the cat.
Successful resuscitation of the brain requires complete microcirculatory reperfusion, which, however, may be impaired by activation of blood coagulation after cardiac arrest. The study addresses the question of whether postischemic thrombolysis is effective in reducing cerebral no-reflow phenomenon. ⋯ The present data demonstrate that thrombolytic therapy improves microcirculatory reperfusion of the cat brain when administered during reperfusion after cardiac arrest.
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Intensive care medicine · Oct 1996
ReviewBedside burr hole for intracranial pressure monitoring performed by intensive care physicians. A 5-year experience.
To assess the results of a 5-year experience with bedside burr hole for intracranial pressure (ICP) monitoring performed by intensive care physicians. ⋯ Bedside insertion of a ICP monitor performed by intensive care physicians is a safe procedure, with a complication rate comparable to other series published by neurosurgeons. The overall morbidity rate is comparable to, or even lower than, that caused by central vein catheterization.
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Intensive care medicine · Oct 1996
Clinical Trial Controlled Clinical TrialClinical consequences of the implementation of a weaning protocol.
To analyze the clinical and economic consequences of the implementation of a weaning protocol in patients mechanically ventilated (MV) for more than 48 h. ⋯ The implementation of a weaning protocol decreased the duration of MV and ICU stay by increasing the number of safe, direct extubations.
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Intensive care medicine · Oct 1996
Validation of a quality of life questionnaire for critically ill patients.
Development and validation of quality of life questionnaire for critical care patients. ⋯ Questionnaire meets objectives recommended for critical care use, and fulfills essential requirements of validity and reproducibility when applied to critically ill patients.