Intensive care medicine
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Intensive care medicine · Jul 1995
Randomized Controlled Trial Comparative Study Clinical TrialGastric emptying following brain injury: effects of choice of sedation and intracranial pressure.
To compare the effects of opioid and non-opioid sedation on gastric emptying. ⋯ Gastric emptying is not improved in patients with brain injury by avoiding morphine (1-8 mg/h) in the sedative regimen. Intracranial hypertension is associated with reduced gastric emptying.
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Intensive care medicine · Jul 1995
Clinical TrialMechanisms of postoperative prolonged plasma volume expansion with low molecular weight hydroxethy starch (HES 200/0.62, 6%).
To define the mechanisms of the stable and prolonged post-operative plasma volume expansion observed with Hydroxyethyl Starches (HES) and to determine whether a partial intravascular hydrolysis of large molecules contribute to reinforce the colloid-osmotic effect. ⋯ Initial plasma volume expansion and decrease in HES concentration agree with previously-published data. Maintenance of plasma volume expansion over 24 h was not related to a partial intravascular hydrolysis. Low elimination rate of HES, extravascular mobilization of albumin and post-operative renal adaptations were possibly the 3 main mechanisms to explain a prolonged plasma volume expansion with HES 200/0.62, 6%.
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Intensive care medicine · Jul 1995
Early jugular bulb oxygenation monitoring in comatose patients after an out-of-hospital cardiac arrest.
To determine the role of early jugular bulb oxygenation monitoring in comatose patients after cardiac arrest. ⋯ Jugular bulb oxygenation monitoring during the first few hours after cardiac arrest cannot reliably discriminate between comatose patients with a good and poor cerebral outcome. Further studies with an extended monitoring period are thus required.
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Intensive care medicine · Jul 1995
P0.1 is a useful parameter in setting the level of pressure support ventilation.
The purpose of this study was to investigate whether changes in breathing pattern, neuromuscular drive (P0.1), and the work involved in breathing might help to set the individual appropriate level of pressure support ventilation (PSV) in patients with acute respiratory failure (ARF) requiring ventilatory assistance. ⋯ During pressure support ventilation, P0.1 may be a more sensitive parameter than the assessment of breathing pattern in setting the optimal level of pressure support in individual patients. Although P0.1 was measured with an esophageal balloon in the present study, non-invasive techniques can also be used.
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Intensive care medicine · Jun 1995
Comparative StudyBlood filtration in children with severe sepsis: safe adjunctive therapy.
To review the safety and efficacy of haemofiltration and plasmafiltration in children with severe sepsis. ⋯ Haemofiltration or plasmafiltration can be performed safely in children with severe sepsis but their effect on outcome remains unknown.