Intensive care medicine
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Intensive care medicine · Mar 1995
Comparative Study Retracted PublicationAlterations in circulating vasoactive substances in the critically ill--a comparison between survivors and non-survivors.
Regulation of circulatory homeostasis is based on several factors including various circulating vasoactive substances. Whether these regulators differ between survivors and non-survivors was investigated in critically ill patients. ⋯ Systemic and regional regulators of the circulation were markedly changed by critical illness. In survivors, these regulators almost normalized within the study period of 5 days, whereas in non-survivors these alterations were even aggravated. It can only be speculated whether these regulator systems were influenced by activation of various mediator systems or whether they themselves influenced the negative outcome in the non-survivors.
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Intensive care medicine · Feb 1995
Comparative StudyClinical validation of the Deltatrac monitoring system in mechanically ventilated patients.
To evaluate a monitor of pulmonary gas exchange (Deltatrac, Datex) in a clinical setting. ⋯ The Deltatrac appears suitable for VO2 and VCO2 measurements in ventilated patients and equivalent to a mass-spectrometer system for long term measurements.
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Successful resuscitation of the brain requires unimpaired blood recirculation. The study addresses the question of the severity and reversibility of no-reflow after cardiac arrest. ⋯ Our observations demonstrate that resuscitation of the heart by closed chest massage causes severe (and after prolonged cardiac arrest irreversible) no-reflow of the brain. This suggests that no-reflow is an important cause of post-resuscitation brain pathology.