Intensive care medicine
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Intensive care medicine · Jan 1993
Hydrogen peroxide in expired breath condensate of patients with acute respiratory failure and with ARDS.
Measurement of hydrogen peroxide concentrations in breath condensate of mechanically ventilated patients with ARDS and with risk factors for developing ARDS. ⋯ Since high concentrations of H2O2 in breath condensate were only found in patients with ARDS or with risk factors for ARDS, the results add to the existing evidence that reactive oxygen species are associated with some acute lung diseases.
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Intensive care medicine · Jan 1993
Randomized Controlled Trial Clinical TrialEffects of extrinsic positive end-expiratory pressure on mechanically ventilated patients with chronic obstructive pulmonary disease and dynamic hyperinflation.
To examine the circulatory and respiratory effects of extrinsic positive end-expiratory pressure (PEEPe) in patients with chronic obstructive pulmonary disease (COPD) and dynamic hyperinflation during controlled mechanical ventilation. ⋯ The effects of PEEPe on iso-volume flow and hence on lung mechanics and hemodynamics, depend on many factors, such as airways resistances, lung volumes and airway characteristics, making the patient response to PEEPe unpredictable.
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Intensive care medicine · Jan 1993
Multicenter StudyIncidence and risk factors of pneumonia acquired in intensive care units. Results from a multicenter prospective study on 996 patients. European Cooperative Group on Nosocomial Pneumonia.
To estimate the incidence of pneumonia acquired in the intensive care unit (ICU), and to define risk factors for developing such an event. ⋯ The role of the injury to the respiratory system-with the subsequent need for respiratory support--appears central in determining the risk to acquire pneumonia in ICU. In the future, the predictive value of severity scores during ICU course should be otherwise assessed.
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Intensive care medicine · Jan 1993
Randomized Controlled Trial Comparative Study Clinical TrialRespiratory response to salbutamol (albuterol) in ventilator-dependent infants with chronic lung disease: pressurized aerosol delivery versus intravenous injection.
To compare the effects of intravenously injected with inhaled salbutamol in ventilator dependent infants with chronic lung disease (CLD). ⋯ Inhaled and intravenous salbutamol improves pulmonary mechanics to the same extent with comparable side effects, and may therefore be used to facilitate weaning from respirators.