Intensive care medicine
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Intensive care medicine · Jan 1993
The effects of norepinephrine on hemodynamics and renal function in severe septic shock states.
To investigate the effect of norepinephrine (NE) on hemodynamics, oxygen metabolism and renal function in patients with severe septic shock. ⋯ Our results suggest that norepinephrine can be used safely in the treatment of severe septic shock states. Mean arterial pressure and glomerular filtration rate improved markedly without deleterious effects on CI, O2AVI and VO2I.
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Intensive care medicine · Jan 1993
Comparative StudyComparison of atracurium and pancuronium in mechanically ventilated neonates.
To compare haemodynamic and gas exchange effects after either atracurium or pancuronium given to ventilated neonates with respiratory failure. ⋯ Both drugs may be used for muscle relaxation in neonates with respiratory failure. Atracurium however causes more cardiovascular depression, whereas the effect of pancuronium may be difficult to predict.
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Intensive care medicine · Jan 1993
Inspiratory pressure/maximal inspiratory pressure ratio: a predictive index of weaning outcome.
To compare the accuracy of PI/PImax ratio and other commonly used indices in predicting weaning outcome. ⋯ The PI/PImax ratio provided a good separation between the patients who were successfully weaned and those who failed. It provides additional discriminative power to f/VT.
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Intensive care medicine · Jan 1993
Comparative StudyComparison of the hemodynamic effects of hydroxocobalamin and cobalt edetate at equipotent cyanide antidotal doses in conscious dogs.
The hemodynamic effects of two cyanide antidotes, hydroxocobalamin and cobalt edetate were compared. ⋯ Considering its lack of hemodynamically relevant effects, these results indicate that hydroxocobalamin is potentially a safer cyanide antidote than cobalt edetate.