Intensive care medicine
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Intensive care medicine · Jan 1993
Histologic aspects of pulmonary barotrauma in critically ill patients with acute respiratory failure.
To describe histologically pulmonary barotrauma in mechanically ventilated patients with severe acute respiratory failure. ⋯ Underlying histologic lesions responsible for clinical lung barotrauma consist of pleural cysts, bronchiolar dilatation, alveolar overdistension and intraprenchymal pseudocysts. Mechanical ventilation appears to be an aggravating factor, particularly when high peak airway pressures and large tidal volumes are delivered by the ventilator.
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Intensive care medicine · Jan 1993
Clinical TrialRight ventricular function in early septic shock states.
To define a variable which could reliably predict when fluid resuscitation as monotherapy is not expected to improve organ perfusion pressure, owing to limitations in cardiac output responsiveness in patients with severe sepsis. ⋯ In 27 septic shock patients investigated, we diagnosed right ventricular dysfunction in 41%. In this specific patient population fluid replacement alone did not succeed in stabilizing hemodynamic variables, therefore necessitating catecholamine therapy.
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Intensive care medicine · Jan 1993
The effects of norepinephrine on hemodynamics and renal function in severe septic shock states.
To investigate the effect of norepinephrine (NE) on hemodynamics, oxygen metabolism and renal function in patients with severe septic shock. ⋯ Our results suggest that norepinephrine can be used safely in the treatment of severe septic shock states. Mean arterial pressure and glomerular filtration rate improved markedly without deleterious effects on CI, O2AVI and VO2I.
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Intensive care medicine · Jan 1993
Inspiratory pressure/maximal inspiratory pressure ratio: a predictive index of weaning outcome.
To compare the accuracy of PI/PImax ratio and other commonly used indices in predicting weaning outcome. ⋯ The PI/PImax ratio provided a good separation between the patients who were successfully weaned and those who failed. It provides additional discriminative power to f/VT.
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Intensive care medicine · Jan 1993
Comparative StudyIntensive use of general ultrasound in the intensive care unit. Prospective study of 150 consecutive patients.
To assess the impact of systematic ultrasound (US) examination in patients admitted to the ICU. ⋯ Routine US examination may alter therapeutic plans in up to 1/4 of critically ill patients admitted to the ICU. US examination should be liberally performed on such patients.